Dopamine Receptor Blockade Attenuates Purinergic P2X4 Receptor-Mediated Prepulse Inhibition Deficits and Underlying Molecular Mechanisms
نویسندگان
چکیده
منابع مشابه
Interaction of Purinergic P2X4 and P2X7 Receptor Subunits
P2X4 and P2X7 are members of the P2X receptor family, comprising seven isoforms (P2X1-P2X7) that form homo- and heterotrimeric non-specific cation channels gated by extracellular ATP. P2X4 and P2X7 are widely coexpressed, particularly in secretory epithelial cells and immune and inflammatory cells, and regulate inflammation and nociception. Although functional heteromerization has been establis...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2019
ISSN: 1662-5102
DOI: 10.3389/fncel.2019.00331